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Clinical Studies


Meal Replacements for Weight Management

  1. Hernandez TL, Ballard RD, Weil KM, et al. Effects of maintained weight loss on sleep dynamics and neck morphology in severely obese adults. Obesity. 2009;17:84-91.
  2. Apovian C, Bigornia S, Cullum-Dugan D, et al. Milk­ based nutritional supplements in conjunction with lifestyle intervention in overweight adolescents. /CAN: Infant, Child, & Adolescent Nutrition. 2009;1:37-44.
  3. Subak LL, Wing R, West OS, et al. Weight loss to treat urinary incontinence in ove!Weight and obese women. N Eng/ J Med. 2009;360:481-490.
  4. Wadden TA, West DS, Neiberg RH, et al. One-year weight losses in the Look AHEAD study: Factors associated with success. Obesity. 2009;17:713-722.
  5. Morgan LM, Griffin BA, Millward OJ, et al. Comparison of the effects of four commercially available weight-loss programmes on lipid-based cardiovascular risk factors. Public Health Nutr. 2009;12:799-807.
  6. Truby H, Hiscutt R, Herriot AM, et al. Commercial weight loss diets meet nutrient requirements in free living adults over 8 weeks: A randomised controlled weight loss trial. Nutr J. 2008;7:25-37.
  7. HerriotAM, Thomas DE, Hart KH, Warren J, Truby H. A qualitative investigation of individuals' experiences and expectations before and after completing a trial of commercial weight loss programmes. J Hum Nutr Diet. 2008;21:72-80.
  8. The Look AHEAD Research Group. Reduction in weight and cardiovascular disease risk factors in individuals with Type 2 diabetes: One-year results of the Look AHEAD trial. Diabetes Care. 2007;30:1374-1383.
  9. Ashley JM, Herzog H, Clodfelter S, Bovee V, Schrage J, Pritsos C. Nutrient adequacy during weight Joss interventions: a randomized study in women comparing the dietary intake in a meal replacement group with a traditional food group. Nutr J. 2007;6:12-20.
  10. Miller, GO, Nicklas, BJ, Davis, C, Loeser, RF, Lenchik, L, Messier, SP. Intensive weight Joss program improves physical function in older obese adults with knee osteoarthritis. Obesity. 2006;14:1219-1230.
  11. Truby H, deLooy A, Fox KR, et al. Randomised controlled trial of four commercial weight Joss programmes in the UK: Initial findings from the BBC "Diet Trials". BMJ. 2006; 332:1309-1314.
  12. Tate DF, Jackvony EH, Wing RR. A randomized trial comparing human e-mail counseling, computer-automated tailored counseling, and no counseling in an internet weight loss program. Arch Intern Med. 2006;166:1620-1625.
  13. Moran LJ, Noakes M, Clifton PM, Witter\GA, Williams G, Norman R. Short-term meal replacements followed by dietary macronutrient restriction enhance weight loss in polycystic ovary syndrome. Am J Clin Nutr. 2006;84:77-87.
  14. Poston WSC, Haddock CK, Pinkston MM, Weight loss with meal replacement and meal replacement plus snacks: A randomized trial. tnt J Obes. 2005;29:1107-1114.
  15. Redmon JB, Reck KP, Raatz SK, et al. Two-year outcome of a combination of weight loss therapies for Type 2 diabetes. Diabetes Care. 2005; 28:1311-1315.
  16. Li Z, Hong K, Saltsman P, et al. Long-term efficacy of soy-based meal replacements vs. an individualized diet plan in obese Type 2 OM patients: relative effects on weight loss, metabolic parameters, and c-reactive protein. Eur J Clin Nutr. 2005;59:411-418.
  17. HuertaS, LiZ, Li HC, HuMS, Yu CA, Heber D. Feasibility of a partial meal replacement plan for weight loss in low-income patients. tnt JObes Relat Metab Disord. 2004;28:1575-1579.
  18. Noakes M, Foster PR, Keogh JB, Clifton PM. Meal replacements are as effective as structured weight­ loss diets for treating obesity in adults with features of metabolic syndrome. J Nutr. 2004;134:1894-1899.
  19. Goode LR, Brolin RE, Chowdhury HA, Shapses
  20. Bone and gastric bypass surgery: effects of dietary calcium and vitamin D. Obes Res. 2004;12:40-47.
  21. Anderson JW, Luan J, Hole LH. Structured weight­ loss programs: Meta-analysis of weight loss at 24 weeks and assessment of effects of intervention intensity. Advances in Therapy. 2004;21:61-75.
  22. Ahrens RA, Hower M, Best AM. Effects of weight reduction interventions by community pharmacists. J Amer Pharm Assoc. 2003;43:583-589.
  23. Dhindsa P, Scott AR, Donnelly R. Metabolic and cardiovascular effects of very-low-calorie diet therapy in obese patients with Type 2 diabetes in secondary failure: outcomes after 1 year. Diabetic Med. 2003;20:319-324.
  24. Redmon JB, Raatz SK, Reck KP, et al. One-year outcome of a combination of weight loss therapies for subjects with Type 2 diabetes mellitus: A randomized trial. Diabetes Care. 2003;26:2505-2511.
  25. Heymsfield SB, van Mierlo CAJ, van der Knaap HCM, Frier HI . Weight management using a meal replacement strategy: Meta and pooling analysis from six studies. lnt J Obes. 2003;27:537-549.
  26. Mattes RD. Feeding behaviors and weight loss outcomes over 64 months. Eating Behaviors. 2002;3:191-204.
  27. Anderson JW, Greenway FL, Fujioka K, Gadde KM, McKenney J, O'Neil PM. Bupropion SR enhances weight loss: A 48-week double-blind, placebo-controlled trial. Obes Res. 2002;10:633-641.
  28. Rothacker DQ, Ellis PK. Elevated intakes of calcium and Vitamin D without added calories and fat in overweight adults: A crossover study in Wisconsin. Current Therapeutic Research. 2002;63:507-512.
  29. Ditschuneit HH, Frier HI, Flechtner-Mors M. Lipoprotein responses to weight loss and weight maintenance in high-risk obese subjects. Eur J Clin Nutr. 2002;56:264-270.
  30. Winick C, Rothacker DQ, Norman RL. Four worksite weight loss programs with high-stress occupations using a meal replacement product. Occup Med. 2002;52:25-30.
  31. Huerta S, Heber D, Sawicki MP, et al. Reduced length of stay by implementation of a clinical pathway for bariatric surgery in an academic health care center. The American Surgeon. 2001;67:1128-1135.
  32. Mattes RD, Rothacker D. Beverage viscosity is inversely related to postprandial hunger in humans. Physiology & Behavior. 2001;74:551-557.
  33. Suarez FL, Zumarraga LM, Furne JK, Levitt MD . Nutritional supplements used in weight­ reduction programs increase intestinal gas in persons who malabsorb lactose. JAm Diet Assoc. 2001;101:1447-1452.
  34. Hensrud DD. Dietary treatment and long-term weight loss and maintenance in Type 2 diabetes. Obes Res. 2001;9:348S-353S.
  35. Ditschuneit HH and Flechtner-Mors M. Value of (structured meals for weight management: Risk factors and long-term weight maintenance. Obes Res. 2001;9:284S-289S.
  36. Ashley JM, St. Jeor ST, Perumean-Chaney S, Scrage J, Bovee V. Meal replacements in weight intervention. Obes Res. 2001;9:312S-320S.
  37. Bowerman S, Bellman M, Saltsman P, et al.Implementation of a primary care physician network obesity management program. Obes Res. 2001; 9:321S-325S.
  38. Yip I, Liang W V, DeShields S, et al. Liquid meal replacement and glycemic control in obese Type 2 diabetes patients. Obes Res. 2001;9:341S-347S.
  39. Ashley JM, St. Jeor ST, Schrage JP, et al. Weight control in the physician's office. Arch Intern Med. 2001;161:1599-1604.
  40. Rothacker DQ, Staniszewski BA, Ellis PK. Liquid meal replacement vs. traditional food: A potential model for women who cannot maintain eating habit change. JAm Die/Assoc. 2001;101:345-347.
  41. Flechtner-Mors M, Ditschuneit HH, Johnson TD,Suchard MA, Adler G. Metabolic and Weight Loss Effects of long-term dietary intervention in obese patients: four-year results. Obes Res. 2000;8:399-402.
  42. Rothacker DQ. Five-year self-management of weight using meal replacements: Comparison with matched controls in rural Wisconsin. Nutrition. 2000;16:344-348.
  43. Ditschuneit HH, Flechtner-Mors M, Johnson TD, Adler G. Metabolic and weight-loss effects of a long-term dietary intervention in obese patients. Am J Clin Nutr. 1999;69:198-204.
  44. Pietrobelli A, Rothacker D, Gallagher D, Heymsfield SB. Electrocardiographic QTc interval: short-term weight loss effects. In! J Obes.1997;21:110-114.
  45. Heber D, Ashley JM, Wang HJ, Elashoff RM. Clinical evaluation of a minimal intervention meal replacement regimen for weight reduction. JAm Col/ Nulr.1994;13:608-614.
  46. Wallner PE, Endersbe LA, Marlin RL. Nutritional supplementation in two high-risk cancer populations. Current Therapeutic Research. 1990;47:924-932.
  47. Smith T, Sigrist L, Bathalon G, et al. Efficacy of Meal-Replacement Program for Promoting Blood Lipid Changes and Weight and Body Fat Loss in US Army Soldiers. JAm Diet Assoc. 2010;110:268-273.
  48. Berkowitz R, Wadden T, Gehrman C, et al. Meal Replacements in the Treatment of Adolescent Obesity: A Randomized Controlled Trial. Obesity. 2011;19:1193-1199.
  49. Wadden T. A Look AHEAD Study: A description of the Lifestyle Intervention and Evidence Supporting It. Obesity. 2006;14:737-752.
  50. Wadden T, West D, Neiberg R, et al. One-Year Weight Losses in Look AHEAD Study: Factors Associated with Success. Obesity. 2009;17:713-722.
  51. Philippou E, Neary N, Chaudhri O, et al. The Effect of Dietary Glycemic Index on Weight Mainenance in Overweight Subjects: A Pilot Study. Obesity. 2008;17:396-401.

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