They sure can! The Diabetic Weight Loss Shake Mixes can be used as a meal replacement option while following the SlimFast Plan, which consists of replacing two meals per day with a SlimFast meal replacement (for breakfast, lunch or dinner), three 100-calorie snacks throughout the day, and one sensible meal. You can eat throughout the day however your schedule permits. For more details on how the SlimFast Plan works, please visit: www.slimfast.com/how-it-works/.